Selective D1 partial agonist. Active enantiomer of (±)-SKF-38393.
Biological descriptionSelective D1 receptor partial agonist. Active enantiomer of (±)-SKF-38393 (ab120740).
Chemical name(R)-(+)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrochloride
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
References for (R)-(+)-SKF38393 hydrochloride (ab120619)
This product has been referenced in:
Chen XQ et al. Arylbenzazepines are potent modulators for the delayed rectifier K+ channel: a potential mechanism for their neuroprotective effects. PLoS One4:e5811 (2009).
Read more (PubMed: 19503734) »
Desai RI et al. Behavioral effects of the R-(+)- and S-(-)-enantiomers of the dopamine D(1)-like partial receptor agonist SKF 83959 in monkeys. Eur J Pharmacol558:98-106 (2007).
Read more (PubMed: 17207791) »
Desai RI et al. Pharmacological characterization of the effects of dopamine D(1) agonists on eye blinking in rats. Behav Pharmacol18:745-54 (2007).
Read more (PubMed: 17989512) »