Overview

  • Product name
  • Description
    Goat polyclonal to RAB11FIP1
  • Specificity
    This antibody is expected to recognise isoform 1 (NP_079427.3) and isoform 3 (NP_001002814.1).
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    EATKEAKESKKPE

    , corresponding to Internal sequence amino acids 418-430 of Human RAB11FIP1

  • Positive control
    • HeLa cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab36124 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 80 kDa (predicted molecular weight: 71 kDa). The observed molecular weight of 80kDa corresponds to earlier findings in literature with different antibodies (Lindsay et al, J Biol Chem. 2002 Apr 5;277(14):12190-9. PMID 11786538.).

Target

  • Function
    A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis.
  • Tissue specificity
    Isoform 2 is expressed in brain, heart, testis, lung, spleen, ovary and small intestine.
  • Sequence similarities
    Contains 1 C2 domain.
    Contains 1 FIP-RBD domain.
  • Cellular localization
    Recycling endosome. Rab11A rather than Rab4A mediates localization in the endocytic recycling compartment (ERC) and Cytoplasmic vesicle, phagosome membrane. Membrane-bound (isoform 2). Colocalizes with Rab11A at phagosomes (isoform 2).
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ22524 antibody
    • FLJ22622 antibody
    • HGNC:30265 antibody
    • MGC78448 antibody
    • No Rab11 binding protein 1A antibody
    • NOEL1A antibody
    • Rab coupling protein antibody
    • Rab effector protein antibody
    • Rab interacting recycling protein antibody
    • Rab-coupling protein antibody
    • RAB11 family interacting protein 1 (class I) antibody
    • Rab11 family interacting protein 1D antibody
    • Rab11 family-interacting protein 1 antibody
    • Rab11 FIP1 antibody
    • Rab11-FIP1 antibody
    • RAB11FIP1 antibody
    • RCP antibody
    • RFIP1_HUMAN antibody
    see all

Images

References

ab36124 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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