Overview

  • Product name
  • Description
    Rabbit polyclonal to RAB13
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Recombinant fragment
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide corresponding to N-terminal residues of human RAB13.

Properties

Applications

Our Abpromise guarantee covers the use of ab55889 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 23 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

Target

  • Function
    Could participate in polarized transport, in the assembly and/or the activity of tight junctions.
  • Tissue specificity
    Detected in several types of epithelia, including intestine, kidney, liver and in endothelial cells.
  • Sequence similarities
    Belongs to the small GTPase superfamily. Rab family.
  • Cellular localization
    Cell junction > tight junction. Cell membrane. Cytoplasmic vesicle membrane. Cytoplasmic tight junctions or associated with vesicles scattered throughout the cytoplasm in cells lacking tight junctions.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cell growth-inhibiting gene 4 protein antibody
    • GIG4 antibody
    • Growth inhibiting gene 4 protein antibody
    • RAB13 antibody
    • RAB13 member RAS oncogene family antibody
    • RAB13_HUMAN antibody
    • RAS associated protein RAB13 antibody
    • Ras related protein Rab13 antibody
    • Ras-related protein Rab-13 antibody
    see all

References for Anti-RAB13 antibody (ab55889)

This product has been referenced in:
  • Almeida MQ  et al. Activation of cyclic AMP signaling leads to different pathway alterations in lesions of the adrenal cortex caused by germline PRKAR1A defects versus those due to somatic GNAS mutations. J Clin Endocrinol Metab 97:E687-93 (2012). WB ; Human . Read more (PubMed: 22259056) »

See 1 Publication for this product

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample
Human Tissue sections (Colon)
Specification
Colon
Fixative
Paraformaldehyde
Antigen retrieval step
Heat mediated - Buffer/Enzyme Used: Novocastra pH 6 retrieval buffer
Permeabilization
No
Blocking step
(agent) for 10 minute(s) · Concentration: 3% · Temperature: 22°C
Username

Dr. Aamir Ahmed

Verified customer

Submitted Jan 25 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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