Overview

  • Product name
    Anti-Rabenosyn 5 antibody - C-terminal
    See all Rabenosyn 5 primary antibodies
  • Description
    Rabbit polyclonal to Rabenosyn 5 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to a region within the C terminal amino acids 721-784 of the Human Rabenosyn 5 protein (Q9H1K0).

  • Positive control
    • WB: A431, H1299, HeLa and HepG2 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab155247 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 89 kDa.

Target

  • Function
    Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3).
  • Sequence similarities
    Contains 1 C2H2-type zinc finger.
    Contains 1 FYVE-type zinc finger.
    Contains 1 UIM (ubiquitin-interacting motif) repeat.
  • Cellular localization
    Cell membrane. Early endosome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 110 kDa protein antibody
    • FYVE finger containing Rab5 effector protein Rabenosyn 5 antibody
    • FYVE finger-containing Rab5 effector protein rabenosyn-5 antibody
    • Rabenosyn-5 antibody
    • RBNS5_HUMAN antibody
    • Zfyve20 antibody
    • zinc finger FYVE domain containing 20 antibody
    • Zinc finger FYVE domain-containing protein 20 antibody
    see all

Images

  • All lanes : Anti-Rabenosyn 5 antibody - C-terminal (ab155247) at 1/1000 dilution

    Lane 1 : H1299 whole cell lysate
    Lane 2 : Hela whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 89 kDa



    7.5% SDS PAGE

References

This product has been referenced in:
  • Frittoli E  et al. A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination. J Cell Biol 206:307-28 (2014). Read more (PubMed: 25049275) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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