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Rabbit polyclonal to Rabenosyn 5 - C-terminal
Recombinant fragment corresponding to a region within the C terminal amino acids 721-784 of the Human Rabenosyn 5 protein (Q9H1K0).
WB: A431, H1299, HeLa and HepG2 whole cell lysates.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 89 kDa.
Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3).
Contains 1 C2H2-type zinc finger.
Contains 1 FYVE-type zinc finger. Contains 1 UIM (ubiquitin-interacting motif) repeat.
Cell membrane. Early endosome membrane.
Information by UniProt
110 kDa protein antibody
FYVE finger containing Rab5 effector protein Rabenosyn 5 antibody
FYVE finger-containing Rab5 effector protein rabenosyn-5 antibody
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