Human Predicted to work with:
Mouse, Rat, Chicken
Recombinant fragment: KSQQLESLQE IKISLEEQLK KETAAKATVE QLMFEEKNKA QRLQTELDVS EQVQRDFVKL SQTLQVQLER IRQADSLERI RAILNDTKLT DINQLPET, corresponding to amino acids 765-863 of Human RABEP1 (NP_004694) with a 26 kDa tag
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 99 kDa.
Use at an assay dependent dilution.
RelevanceRABEP1 is a Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. It is involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A.
Cellular localizationCytoplasm. Early endosome. Recycling endosome