Overview

  • Product name
  • Description
    Mouse polyclonal to RABL4
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    RABL4 full-length human protein.

  • Positive control
    • RABL4 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab67909 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 20 kDa).

Target

  • Function
    Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6 (PubMed:25443296). Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6 (PubMed:25443296). Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25.
  • Involvement in disease
    Bardet-Biedl syndrome 19
  • Sequence similarities
    Belongs to the small GTPase superfamily. Rab family.
  • Cellular localization
    Cell projection, cilium.
  • Information by UniProt
  • Database links
  • Alternative names
    • BBS19 antibody
    • Ift27 antibody
    • IFT27_HUMAN antibody
    • Intraflagellar transport 27 antibody
    • Intraflagellar transport protein 27 homolog antibody
    • Putative GTP binding protein RAY like antibody
    • Putative GTP-binding protein RAY-like antibody
    • Rab like protein 4 antibody
    • RAB member of RAS oncogene family like 4 antibody
    • Rab-like protein 4 antibody
    • RAYL antibody
    see all

Images

  • All lanes : Anti-RABL4 antibody (ab67909) at 1/500 dilution

    Lane 1 : RABL4 transfected 293T cell lysate
    Lane 2 : non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 20 kDa
    Observed band size : 25 kDa (why is the actual band size different from the predicted?)

References

ab67909 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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