• Product name
    Anti-RAC antibody [23A8]
  • Description
    Mouse monoclonal [23A8] to RAC
  • Specificity
    ab13048 recognizes Rac1 with a slight Rac2 cross-reactivity.
  • Tested applications
    Suitable for: IHC-Fr, IP, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length Human RAC1.

  • General notes
    Storage in frost-free freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.



Our Abpromise guarantee covers the use of ab13048 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr Use a concentration of 10 µg/ml.
IP Use at an assay dependent concentration.
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 21 kDa.


  • Relevance
    RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.
  • Cellular localization
    Cell Membrane
  • Database links
  • Alternative names
    • MIG5 antibody
    • Migration inducing gene 5 antibody
    • p21 Rac1 antibody
    • RAC1 antibody
    • Ras like protein TC25 antibody
    see all

References for Anti-RAC antibody [23A8] (ab13048)

This product has been referenced in:
  • Ghosh S  et al. Endoplasmic Reticulum Resident Heat Shock Protein 90 (Hsp90) Isoform Glucose-Regulated Protein 94 (Grp94) Regulates Cell Polarity and Cancer Cell Migration by Affecting Intracellular Transport. J Biol Chem N/A:N/A (2016). WB ; Human . Read more (PubMed: 26872972) »
  • Zhang X  et al. Digital gene expression tag profiling analysis of the gene expression patterns regulating the early stage of mouse spermatogenesis. PLoS One 8:e58680 (2013). WB ; Mouse . Read more (PubMed: 23554914) »

See all 5 Publications for this product

Product Wall

Thank you for your enquiry. Unfortunately this antibody has not been tested for specificity between the different RAC isoforms. I hope this information helps, please do not hesitate to contact us if you need any more advice or information.


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