Overview

  • Product nameAnti-RAC2 antibody (HRP)
    See all RAC2 primary antibodies
  • Description
    Goat polyclonal to RAC2 (HRP)
  • ConjugationHRP
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    PQPTRQQKRACSLL

    , corresponding to C terminal amino acids 179-192 of Human RAC2 according to NP_002863.1.

  • Positive control
    • MOLT4 lysates.
  • General notes

    Conjugated via amine groups to horseradish peroxidise.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferPreservative: 0.1% Proclin
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab124168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 21 kDa.

Target

  • FunctionPlasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
  • Tissue specificityHematopoietic specific.
  • Involvement in diseaseDefects in RAC2 are the cause of neutrophil immunodeficiency syndrome (NEUID) [MIM:608203].
  • Sequence similaritiesBelongs to the small GTPase superfamily. Rho family.
  • Cellular localizationCytoplasm. Membrane-associated when activated.
  • Information by UniProt
  • Database links
  • FormRac2 has high sequence homology with other Rac proteins. Therefore some antibodies may show cross-reactivity.
  • Alternative names
    • EN 7 antibody
    • EN-7 antibody
    • EN7 antibody
    • GX antibody
    • HSPC 022 antibody
    • HSPC022 antibody
    • p21 Rac 2 antibody
    • p21 Rac2 antibody
    • p21-Rac2 antibody
    • p21Rac2 antibody
    • RAC 2 antibody
    • Rac2 antibody
    • RAC2_HUMAN antibody
    • Ras related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2 antibody
    • Ras related C3 botulinum toxin substrate 2 antibody
    • Ras related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac2) antibody
    • Ras related C3 botulinum toxin substrate 3 antibody
    • Ras-related C3 botulinum toxin substrate 2 antibody
    • Rho family small GTP binding protein Rac 2 antibody
    • Rho family small GTP binding protein Rac2 antibody
    • Small G protein antibody
    see all

Anti-RAC2 antibody (HRP) images

  • Anti-RAC2 antibody (HRP) (ab124168) at 1/1000 dilution + MOLT4 cell lysates at 35 µg
    Developed using the ECL technique

    Predicted band size : 21 kDa

References for Anti-RAC2 antibody (HRP) (ab124168)

ab124168 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"