Overview

  • Product nameAnti-RAD18 antibody
    See all RAD18 primary antibodies
  • Description
    Rabbit polyclonal to RAD18
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 1 - 229 of Human RAD18 (AAH01302).

  • Positive control
    • WB: 293T, H1299, HeLa, HepG2, MOLT4 or Raji cell lysate; IHC-P: Cal27 xenograft tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab97670 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 56 kDa.
IHC-P 1/100 - 1/250.

Target

  • FunctionE3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesBelongs to the RAD18 family.
    Contains 1 RING-type zinc finger.
    Contains 1 SAP domain.
    Contains 1 UBZ-type zinc finger.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2810024C04Rik antibody
    • DNA repair protein rad18 antibody
    • E3 ubiquitin-protein ligase RAD18 antibody
    • EC 6.3.2.- antibody
    • hHR 18 antibody
    • hHR18 antibody
    • hRAD 18 antibody
    • hRAD18 antibody
    • MGC156682 antibody
    • Postreplication repair E3 ubiquitin-protein ligase RAD18 antibody
    • Postreplication repair protein hRAD18p antibody
    • Postreplication repair protein RAD18 antibody
    • RAD 18 antibody
    • RAD18 antibody
    • RAD18 homolog (S. cerevisiae) antibody
    • RAD18 homolog antibody
    • RAD18 S. cerevisiae homolog antibody
    • RAD18 S. cerevisiae homolog of antibody
    • RAD18 transcript variant antibody
    • RAD18_HUMAN antibody
    • Rad18sc antibody
    • Radiation sensitivity protein 18 antibody
    • RING finger protein 73 antibody
    • RNF 73 antibody
    • RNF73 antibody
    • Structural maintenance of chromosomes protein 6 antibody
    • YCR066W antibody
    • YCR66W antibody
    see all

Anti-RAD18 antibody images

  • Anti-RAD18 antibody (ab97670) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 56 kDa
  • ab97670 at 1/100 dilution staining RAD18 in paraffin-embedded Cal27 xenograft tissue by immunohistochemistry.

References for Anti-RAD18 antibody (ab97670)

ab97670 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"