Anti-Rad51L1 antibody [Rad51B 1H3/13] (ab20242)

Overview

  • Product name
    Anti-Rad51L1 antibody [Rad51B 1H3/13]
    See all Rad51L1 primary antibodies
  • Description
    Mouse monoclonal [Rad51B 1H3/13] to Rad51L1
  • Specificity
    Does not recognise Rad51C in total HeLa extracts.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein (Human) that has been his-tagged and overexpressed in e.coli.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    IgG fraction
  • Purification notes
    The antibody was purified on a talon affinity column under denaturing conditions, followed by gel purification on a SDS-Page.
  • Clonality
    Monoclonal
  • Clone number
    Rad51B 1H3/13
  • Myeloma
    Sp2/0-Ag14
  • Isotype
    IgG2a
  • Light chain type
    unknown
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab20242 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 38 kDa.

Target

  • Function
    Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. The RAD51B-RAD51C dimer exhibits single-stranded DNA-dependent ATPase activity. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
  • Tissue specificity
    Expressed in a wide range of tissues.
  • Involvement in disease
    Note=A chromosomal aberration involving RAD51L1 is found in pulmonary chondroid hamartoma. Translocation t(6;14)(p21;q23-24) with HMGA1.
    Note=A chromosomal aberration involving RAD51L1 is found in uterine leiomyoma. Translocation t(12;14)(q15;q23-24) with HMGA2.
  • Sequence similarities
    Belongs to the RecA family. RAD51 subfamily.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DNA repair protein RAD51 homolog 2 antibody
    • hREC2 antibody
    • MGC34245 antibody
    • OTTHUMP00000212251 antibody
    • OTTHUMP00000212253 antibody
    • OTTHUMP00000212254 antibody
    • OTTHUMP00000212255 antibody
    • R51H2 antibody
    • RA51B_HUMAN antibody
    • RAD51 homolog B (S. cerevisiae) antibody
    • RAD51 homolog B antibody
    • RAD51 like 1 antibody
    • RAD51 like protein 1 antibody
    • RAD51-like protein 1 antibody
    • Rad51B antibody
    • RAD51L1 antibody
    • REC2 antibody
    • RecA like protein antibody
    • Recombination repair protein antibody
    see all

References

ab20242 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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