Anti-Rad51L1 antibody [Rad51B 1H3/13] (ab20242)

Overview

  • Product nameAnti-Rad51L1 antibody [Rad51B 1H3/13]
    See all Rad51L1 primary antibodies
  • Description
    Mouse monoclonal [Rad51B 1H3/13] to Rad51L1
  • SpecificityDoes not recognise Rad51C in total HeLa extracts.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein (Human) that has been his-tagged and overexpressed in e.coli.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityIgG fraction
  • Purification notesThe antibody was purified on a talon affinity column under denaturing conditions, followed by gel purification on a SDS-Page.
  • ClonalityMonoclonal
  • Clone numberRad51B 1H3/13
  • MyelomaSp2/0-Ag14
  • IsotypeIgG2a
  • Light chain typeunknown
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab20242 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 38 kDa.

Target

  • FunctionInvolved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. The RAD51B-RAD51C dimer exhibits single-stranded DNA-dependent ATPase activity. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
  • Tissue specificityExpressed in a wide range of tissues.
  • Involvement in diseaseNote=A chromosomal aberration involving RAD51L1 is found in pulmonary chondroid hamartoma. Translocation t(6;14)(p21;q23-24) with HMGA1.
    Note=A chromosomal aberration involving RAD51L1 is found in uterine leiomyoma. Translocation t(12;14)(q15;q23-24) with HMGA2.
  • Sequence similaritiesBelongs to the RecA family. RAD51 subfamily.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DNA repair protein RAD51 homolog 2 antibody
    • hREC2 antibody
    • MGC34245 antibody
    • OTTHUMP00000212251 antibody
    • OTTHUMP00000212253 antibody
    • OTTHUMP00000212254 antibody
    • OTTHUMP00000212255 antibody
    • R51H2 antibody
    • RA51B_HUMAN antibody
    • RAD51 homolog B (S. cerevisiae) antibody
    • RAD51 homolog B antibody
    • RAD51 like 1 antibody
    • RAD51 like protein 1 antibody
    • RAD51-like protein 1 antibody
    • Rad51B antibody
    • RAD51L1 antibody
    • REC2 antibody
    • RecA like protein antibody
    • Recombination repair protein antibody
    see all

References for Anti-Rad51L1 antibody [Rad51B 1H3/13] (ab20242)

ab20242 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab20242.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"