Overview

  • Product name
  • Description
    Rabbit polyclonal to RAD54L2
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Chimpanzee, Ferret, Gorilla, Chinese hamster, Elephant
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 75-125 of Human RAD54L2 (NP_055921.2).

  • Positive control
    • Breast Carcinoma, Colon Carcinoma, Non-Small Cell Lung Cancer, Testicular Seminoma

Properties

Applications

Our Abpromise guarantee covers the use of ab96370 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Epitope exposure is recommended, with tris-EDTA pH 9.0 buffer to enhance staining. Likely to work with frozen sections.

Target

  • Function
    DNA helicase that modulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. Not able to remodel mononucleosomes in vitro.
  • Sequence similarities
    Belongs to the SNF2/RAD54 helicase family.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
  • Domain
    Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to be important for the association with nuclear receptors.
  • Post-translational
    modifications
    Sumoylated.
  • Cellular localization
    Nucleus. Localizes in speckle-like nuclear compartments.
  • Information by UniProt
  • Database links
  • Alternative names
    • Androgen receptor interacting protein 4 antibody
    • Androgen receptor-interacting protein 4 antibody
    • Arip4 antibody
    • ARIP4_HUMAN antibody
    • HCMV interacting protein; antibody
    • Helicase ARIP4 antibody
    • HSPC325 antibody
    • RAD54 like 2 (S. cerevisiae) antibody
    • RAD54 like protein 2 antibody
    • RAD54-like protein 2 antibody
    • Rad54l2 antibody
    • SRISNF2L antibody
    • Steroid receptor interacting SNF2 domain protein antibody
    see all

Images

  • ab96370, at 1/250 dilution, staining RAD54L2 in formalin-fixed, paraffin-embedded Human colon carcinoma by Immunohistochemistry using DAB detection.

References

ab96370 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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