Overview

  • Product name
    Anti-RAI3 antibody - N-terminal
    See all RAI3 primary antibodies
  • Description
    Rabbit polyclonal to RAI3 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 1-45 of Human RAI3 (UniProt Q8NFJ5).

  • Positive control
    • 293T, A431, H1299, HeLa, HepG2, Molt-4 and Raji cell lysates; CAL27 xenograft tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 1.21% Tris, 10% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab155557 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 40 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol using 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0).

Target

  • Function
    Unknown. This G-protein coupled receptor could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. The comparable expression level in fetal lung and kidney with adult tissues suggests a possible role in embryonic development and maturation of these organs. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
  • Tissue specificity
    Expressed at high level in fetal and adult lung tissues. Constitutively expressed in fetal kidney and adult placenta, kidney, prostate, testis, ovary, small intestine, colon, stomach, and spinal chord at low to moderate levels. Not detectable in fetal heart, brain, and liver and adult heart, brain, liver, skeletal muscle, pancreas, spleen, thymus, and peripheral leukocytes. According to PubMed:10783259, expressed at low but detectable level in pancreas and heart.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 3 family.
  • Cellular localization
    Cell membrane. Cytoplasmic vesicle membrane. Localized in the plasma membrane and perinuclear vesicles.
  • Information by UniProt
  • Database links
  • Alternative names
    • G protein coupled receptor family C group 5 member A antibody
    • G-protein coupled receptor family C group 5 member A antibody
    • GPCR 5A antibody
    • GPCR5A antibody
    • Gprc 5a antibody
    • Gprc5a antibody
    • Orphan G protein coupling receptor PEIG 1 antibody
    • Orphan G protein coupling receptor PEIG1 antibody
    • Orphan G-protein-coupling receptor PEIG-1 antibody
    • RAI 3 antibody
    • RAI3_HUMAN antibody
    • Raig 1 antibody
    • RAIG-1 antibody
    • Raig1 antibody
    • Retinoic acid induced 3 antibody
    • Retinoic acid induced gene 1 protein antibody
    • Retinoic acid induced protein 3 antibody
    • Retinoic acid responsive antibody
    • Retinoic acid responsive gene antibody
    • Retinoic acid-induced gene 1 protein antibody
    • Retinoic acid-induced protein 3 antibody
    see all

Images

  • All lanes : Anti-RAI3 antibody - N-terminal (ab155557) at 1/1000 dilution

    Lane 1 : H1299 whole cell lysate
    Lane 2 : HeLa whole cell lysate
    Lane 3 : HepG2 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 40 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human CAL27 xenograft tissue labeling RAI3 with ab155557 at 1/100 dilution.

References

ab155557 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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