Overview

  • Product nameAnti-RAIDD antibody
    See all RAIDD primary antibodies
  • Description
    Rabbit polyclonal to RAIDD
  • Specificityab110914 detects an ~24 kD protein, corresponding to the apparent molecular mass of RAIDD on SDS-PAGE immunoblots. This 24 kD band, as well as a 67 kD band, can be specifically inhibited by the relevant peptide.
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Hamster, Monkey
  • Immunogen

    Synthetic peptide, corresponding to a region within Human RAIDD.

  • Positive control
    • Formalin fixed, paraffin embedded Human skeletal muscle. Formalin fixed, paraffin embedded Human placenta. Formalin fixed, paraffin embedded Human testis.

Properties

Applications

Our Abpromise guarantee covers the use of ab110914 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Predicted molecular weight: 23 kDa.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionApoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
  • Tissue specificityConstitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
  • Sequence similaritiesContains 1 CARD domain.
    Contains 1 death domain.
  • DomainContains a death domain involved in the binding of RIP protein.
    The CARD domain mediates the interaction with caspase-2.
  • Information by UniProt
  • Database links
  • Alternative names
    • CASP2 and RIPK1 domain containing adaptor with death domain antibody
    • Caspase and RIP adapter with death domain antibody
    • Caspase and RIP adaptor with death domain antibody
    • Cradd antibody
    • CRADD_HUMAN antibody
    • Death adaptor molecule RAIDD antibody
    • Death domain containing protein CRADD antibody
    • Death domain-containing protein CRADD antibody
    • MGC9163 antibody
    • RIP associated ICH1/CED3 homologous protein with death domain antibody
    • RIP associated protein with a death domain antibody
    • RIP-associated protein with a death domain antibody
    see all

Anti-RAIDD antibody images

  • ab110914, at 10 µg/ml, staining RAIDD in formalin fixed, paraffin embedded Human skeletal muscle tissue by Immunohistochemistry. Biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen was used to develop the staining.
  • ab110914, at 10 µg/ml, staining RAIDD in formalin fixed, paraffin embedded Human placenta tissue by Immunohistochemistry. Biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen was used to develop the staining.
  • ab110914, at 10 µg/ml, staining RAIDD in formalin fixed, paraffin embedded Human testis by Immunohistochemistry. Biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen was used to develop the staining.

References for Anti-RAIDD antibody (ab110914)

ab110914 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"