Overview

  • Product nameAnti-RAIDD antibody [EPR1639]
    See all RAIDD primary antibodies
  • Description
    Rabbit monoclonal [EPR1639] to RAIDD
  • Tested applicationsSuitable for: WB, IP, ICC, Flow Cytmore details
    Unsuitable for: IHC-P
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    A synthetic peptide corresponding to residues in human RAIDD

  • Positive control
    • Raji, HeLa, K562 and MCF7 cell lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Applications

Our Abpromise guarantee covers the use of ab76465 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 23 kDa.
IP 1/40.
ICC 1/100 - 1/250.
Flow Cyt 1/30.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

  • Application notesIs unsuitable for IHC-P.
  • Target

    • FunctionApoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
    • Tissue specificityConstitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
    • Sequence similaritiesContains 1 CARD domain.
      Contains 1 death domain.
    • DomainContains a death domain involved in the binding of RIP protein.
      The CARD domain mediates the interaction with caspase-2.
    • Information by UniProt
    • Database links
    • Alternative names
      • CASP2 and RIPK1 domain containing adaptor with death domain antibody
      • Caspase and RIP adapter with death domain antibody
      • Caspase and RIP adaptor with death domain antibody
      • Cradd antibody
      • CRADD_HUMAN antibody
      • Death adaptor molecule RAIDD antibody
      • Death domain containing protein CRADD antibody
      • Death domain-containing protein CRADD antibody
      • MGC9163 antibody
      • RIP associated ICH1/CED3 homologous protein with death domain antibody
      • RIP associated protein with a death domain antibody
      • RIP-associated protein with a death domain antibody
      see all

    Anti-RAIDD antibody [EPR1639] images

    • All lanes : Anti-RAIDD antibody [EPR1639] (ab76465) at 1/5000 dilution

      Lane 1 : Raji cell lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : K562 cell lysate
      Lane 4 : MCF7 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size : 23 kDa
      Observed band size : 23 kDa

    References for Anti-RAIDD antibody [EPR1639] (ab76465)

    ab76465 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab76465.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"