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Rabbit monoclonal [EPR1640Y] to RAIDD
Synthetic peptide corresponding to residues from the C terminus of human RAIDD.
HeLa cell lysate and Human heart muscle tissue.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab ® patents
This product is a recombinant rabbit monoclonal antibody.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Detects a band of approximately 23 kDa (predicted molecular weight: 23 kDa).
1/100 - 1/250.
ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
Contains 1 CARD domain.
Contains 1 death domain.
Contains a death domain involved in the binding of RIP protein.
The CARD domain mediates the interaction with caspase-2.
Information by UniProt
CASP2 and RIPK1 domain containing adaptor with death domain antibody
Caspase and RIP adapter with death domain antibody
Caspase and RIP adaptor with death domain antibody
Western blot - RAIDD antibody [EPR1640Y] (ab52621)
Anti-RAIDD antibody [EPR1640Y] (ab52621) at 1/1000 dilution + HeLa cell lysate at 10 µg
Secondary goat anti-rabbit HRP at 1/2000 dilution Predicted band size: 23 kDa Observed band size: 23 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAIDD antibody [EPR1640Y] (ab52621)
ab52621, at a 1/50 dilution, staining Human RAIDD in heart muscle, using Immunohistochemistry, Paraffin embedded tissue.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"