This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Overview

Properties

Applications

  • Application notesTested in peptide ELISA. Antibody detection limit dilution 1/8000.
    WB: Use at a concentration of 0.3 µg/ml. Predicted molecular weight: 110 kDa.
    WB experiments gave bands at approx 95kDa, 75kDa and 45kDa in Lung Carcinoma lysate after antibody staining. Please note that currently we cannot find an explanation in the literature for the additional bands we observe given the predicted size according to NP_060275. The detected bands were successfully blocked by incubation with the immunizing peptide.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation.
    • Tissue specificityHighly expressed in heart. Detected at lower levels in placenta and pancreas.
    • Sequence similaritiesContains 1 dilute domain.
      Contains 1 Ras-associating domain.
    • Cellular localizationCytoplasm > perinuclear region. Golgi apparatus > Golgi stack. Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ20401 antibody
      • Rain antibody
      • RAIN protein fragment antibody
      • RAIN_HUMAN antibody
      • Ras interacting protein 1 antibody
      • Ras-interacting protein 1 antibody
      • RASIP 1 antibody
      • RASIP1 antibody
      • RASIP1 protein antibody
      see all

    References for Anti-RAIN antibody (ab21018)

    ab21018 has not yet been referenced specifically in any publications.

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    I am sorry to confirm that because this antibody is a Fast Track antibody, we are not able to provide AbTrial in this case. This is becuase there is a possibility to obtain a large number of Abpoints for submissio...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"