Overview

  • Product nameAnti-RALBP1 antibody [EPR6473]
    See all RALBP1 primary antibodies
  • Description
    Rabbit monoclonal [EPR6473] to RALBP1
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Human
    Does not react with: Mouse, Rat
  • Immunogen

    Synthetic peptide, corresponding to residues near the C-terminus of Human RALBP1.

  • Positive control
    • MCF7, HT29, K562 and Jurkat cell lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Properties

Applications

Our Abpromise guarantee covers the use of ab124816 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 95 kDa (predicted molecular weight: 76 kDa).
  • Application notesIs unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • FunctionCan activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
    • Tissue specificityExpressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes.
    • Sequence similaritiesContains 1 Rho-GAP domain.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • RLIP1 antibody
      • 76 kDa Ral-interacting protein antibody
      • 76-kDa Ral-interacting protein antibody
      • Dinitrophenyl S-glutathione ATPase antibody
      • DNP-SG ATPase antibody
      • Ral-interacting protein 1 antibody
      • Ral-interacting protein 1, 76-KD antibody
      • RalA-binding protein 1 antibody
      • RalBP1 antibody
      • RBP1_HUMAN antibody
      • RIP1 antibody
      • RLIP1 antibody
      • RLIP76 antibody
      see all

    Anti-RALBP1 antibody [EPR6473] images

    • All lanes : Anti-RALBP1 antibody [EPR6473] (ab124816) at 1/1000 dilution

      Lane 1 : MCF7 cell lysate
      Lane 2 : HT29 cell lysate
      Lane 3 : K562 cell lysate
      Lane 4 : Jurkat cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat anti-Rabbit HRP at 1/2000 dilution
      Developed using the ECL technique

      Predicted band size : 76 kDa

    References for Anti-RALBP1 antibody [EPR6473] (ab124816)

    ab124816 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab124816.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"