Overview

  • Product nameAnti-Ran antibody
    See all Ran primary antibodies
  • Description
    Rabbit polyclonal to Ran
  • SpecificityObserved cross-reactivity with ~26 kDa tag.
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Saccharomyces cerevisiae
  • Immunogen

    Recombinant fusion protein (S. cerevisiae).

Properties

Applications

Our Abpromise guarantee covers the use of ab11693 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 26 kDa).
ICC/IF Use at an assay dependent dilution.

Target

  • FunctionGTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.
    Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
  • Tissue specificityExpressed in a variety of tissues.
  • Sequence similaritiesBelongs to the small GTPase superfamily. Ran family.
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Cellular localizationNucleus. Cytoplasm. Melanosome. Becomes dispersed throughout the cytoplasm during mitosis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • Alternative names
    • Androgen receptor associated protein 24 antibody
    • Androgen receptor-associated protein 24 antibody
    • ARA 24 antibody
    • ARA24 antibody
    • Gsp1 antibody
    • GTP binding nuclear protein RAN antibody
    • GTP-binding nuclear protein Ran antibody
    • GTPase Ran antibody
    • Guanosine triphosphatase Ran antibody
    • LPS antibody
    • OK/SW-cl.81 antibody
    • ran antibody
    • RAN member RAS oncogene family antibody
    • RAN_HUMAN antibody
    • RanGTPase antibody
    • Ras like protein TC4 antibody
    • Ras related nuclear protein antibody
    • Ras-like protein TC4 antibody
    • Ras-related nuclear protein antibody
    • RASL2 8 antibody
    • TC 4 antibody
    • TC4 antibody
    see all

Anti-Ran antibody images



  • Predicted band size : 26 kDa


    ab11693 at a 1/1000 dilution staining approximately 25kDa Ran in S.cerevisiae whole cell lysate by Western blot (ECL).

References for Anti-Ran antibody (ab11693)

This product has been referenced in:
  • Muniyappa MK  et al. MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines. Eur J Cancer 45:3104-18 (2009). WB ; Human . Read more (PubMed: 19818597) »

See 1 Publication for this product

Product Wall

Thank you for contacting us. Unfortunately, other than ab11693 which cross-reacts with the 26 kDa tag, our other Ran antibodies are raised against human Ran. Most would be unlikely to cross-react with yeast, due to low sequence homology with their immu...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"