Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab2937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 24 kDa).Can be blocked with RanBP1 peptide (ab4938).

Target

  • FunctionInhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane.
  • Sequence similaritiesBelongs to the RANBP1 family.
    Contains 1 RanBD1 domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • HTF9A antibody
    • RAN binding protein 1 antibody
    • Ran specific GTPase activating protein antibody
    • Ran-binding protein 1 antibody
    • Ran-specific GTPase-activating protein antibody
    • RANBP1 antibody
    • RANG_HUMAN antibody
    see all

Anti-RanBP1 antibody images

  • All lanes : Anti-RanBP1 antibody (ab2937) at 1/1000 dilution

    Lane 1 : HeLa cell lysate
    Lane 2 : Human brain tissue lysate
    Lane 3 : NIH-3T3 cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    HRP conjugated anti-rabbit
    Developed using the ECL technique

    Predicted band size : 24 kDa
    Observed band size : 27 kDa (why is the actual band size different from the predicted?)


    Exposure time : 1 minute

References for Anti-RanBP1 antibody (ab2937)

This product has been referenced in:
  • Schulz M  et al. Proteomic analysis of peripheral blood mononuclear cells: selective protein processing observed in patients with rheumatoid arthritis. J Proteome Res 6:3752-9 (2007). WB ; Human . Read more (PubMed: 17705417) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"