Overview

  • Product name
  • Description
    Goat polyclonal to RanBP16
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide: NSTYGVNSNDMMS, corresponding to C terminal amino acids 1075-1087 of Human RanBP16.

  • Positive control
    • Hela lysate and Human Testis Lysate.
  • General notes
    GenBank Accession Number – NP_055839.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris-saline. pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab6041 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 124 kDa).Can be blocked with Human RanBP16 peptide (ab23146).

Target

  • Relevance
    The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex. The small GTPase RAN plays a key role in NLS-dependent protein import. RAN-binding protein-16 is a member of the importin-beta superfamily of nuclear transport receptors.
  • Cellular localization
    Cytoplasm. Nucleus. Nucleus; nuclear pore complex. Note: Shuttles between the nucleus and the cytoplasm
  • Database links
  • Alternative names
    • Exp 7 antibody
    • Exp7 antibody
    • Exportin 7 antibody
    • Exportin7 antibody
    • KIAA0745 antibody
    • RAN binding protein 16 antibody
    • RANBP 16 antibody
    • XPO 7 antibody
    • XPO7 antibody
    see all

Images



  • Predicted band size : 124 kDa


    ab6041 at 0.5µg/ml staining approximately 110kDa band of RANBP16 in HeLa Lysate by Western blot (ECL).

References

ab6041 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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