The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/10000. Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa).
Application notesIs unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
FunctionInduces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner.
Sequence similaritiesBelongs to the small GTPase superfamily. Ras family.