Overview

  • Product nameAnti-RAP1GAP2 antibody
  • Description
    Rabbit polyclonal to RAP1GAP2
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 700-730 of Human RAP1GAP2

  • Positive control
    • HeLa cell lysate, Mouse brain tissue lysate, Human pancreas tissue

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab104176 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 80 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionGTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.
  • Tissue specificityIsoform 1 and isoform 2 are expressed in platelets with isoform 2 being the predominant form. Expressed in lymphocytes, heart, testis and pancreas.
  • Sequence similaritiesContains 1 Rap-GAP domain.
  • Post-translational
    modifications
    In vitro phosphorylated by cGMP-dependent protein kinase 1 (cGKI) at Ser-7; the phosphorylation probably does not regulate GAP activity.
  • Cellular localizationCytoplasm. Cytoplasm, perinuclear region.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp686O238 antibody
    • GARNL4 antibody
    • GTPase activating RANGAP domain like 4 antibody
    • GTPase activating Rap/RanGAP domain like 4 antibody
    • GTPase activating Rap/RanGAP domain like protein 4 antibody
    • GTPase-activating Rap/Ran-GAP domain-like protein 4 antibody
    • KIAA1039 antibody
    • RAP1 GTPase activating protein 2 antibody
    • Rap1 GTPase-activating protein 2 antibody
    • RAP1GA3 antibody
    • Rap1GAP2 antibody
    • RPGP2_HUMAN antibody
    see all

Anti-RAP1GAP2 antibody images

  • Anti-RAP1GAP2 antibody (ab104176) at 1/100 dilution + HeLa cell lysate at 35 µg

    Predicted band size : 80 kDa
  • Anti-RAP1GAP2 antibody (ab104176) at 1/100 dilution + Mouse brain tissue lysate at 35 µg/ml

    Predicted band size : 80 kDa
  • ab104176, at 1/50 dilution, staining RAP1GAP2 in formalin fixed and paraffin embedded Human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

References for Anti-RAP1GAP2 antibody (ab104176)

ab104176 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"