Overview

  • Product nameAnti-RASSF2 antibody [EPR6621]
    See all RASSF2 primary antibodies
  • Description
    Rabbit monoclonal [EPR6621] to RASSF2
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues at the C terminus of Human RASSF2.

  • Positive control
    • Raji, Jurkat and SH-SY5Y cell lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab124786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 37 kDa.
  • Application notesIs unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • FunctionPotential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest.
    • Tissue specificityWidely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.
    • Sequence similaritiesContains 1 Ras-associating domain.
      Contains 1 SARAH domain.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • CENP 34 antibody
      • Centromere protein 34 antibody
      • Ras association (RalGDS/AF 6) domain family 2 antibody
      • Ras association (RalGDS/AF-6) domain family member 2 antibody
      • Ras association domain containing protein 2 antibody
      • Ras association domain-containing protein 2 antibody
      • RASF2_HUMAN antibody
      • RASFADIN antibody
      • RASSF2 antibody
      • RP4-599I11.1 antibody
      see all

    Anti-RASSF2 antibody [EPR6621] images

    • All lanes : Anti-RASSF2 antibody [EPR6621] (ab124786) at 1/1000 dilution

      Lane 1 : Raji cell lysate
      Lane 2 : Jurkat cell lysate
      Lane 3 : SH-SY5Y cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Standard HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 37 kDa
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References for Anti-RASSF2 antibody [EPR6621] (ab124786)

    This product has been referenced in:
    • Guerrero-Setas D  et al. RASSF2 hypermethylation is present and related to shorter survival in squamous cervical cancer. Mod Pathol N/A:N/A (2013). IHC ; Human . Read more (PubMed: 23542458) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab124786.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"