Overview

  • Product name
    Anti-RASSF2 antibody [EPR6621]
    See all RASSF2 primary antibodies
  • Description
    Rabbit monoclonal [EPR6621] to RASSF2
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues at the C terminus of Human RASSF2.

  • Positive control
    • Raji, Jurkat and SH-SY5Y cell lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab124786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 37 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function
      Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest.
    • Tissue specificity
      Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.
    • Sequence similarities
      Contains 1 Ras-associating domain.
      Contains 1 SARAH domain.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • CENP 34 antibody
      • Centromere protein 34 antibody
      • Ras association (RalGDS/AF 6) domain family 2 antibody
      • Ras association (RalGDS/AF-6) domain family member 2 antibody
      • Ras association domain containing protein 2 antibody
      • Ras association domain-containing protein 2 antibody
      • RASF2_HUMAN antibody
      • RASFADIN antibody
      • RASSF2 antibody
      • RP4-599I11.1 antibody
      see all

    Images

    • All lanes : Anti-RASSF2 antibody [EPR6621] (ab124786) at 1/1000 dilution

      Lane 1 : Raji cell lysate
      Lane 2 : Jurkat cell lysate
      Lane 3 : SH-SY5Y cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Standard HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 37 kDa
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    This product has been referenced in:
    • Guerrero-Setas D  et al. RASSF2 hypermethylation is present and related to shorter survival in squamous cervical cancer. Mod Pathol N/A:N/A (2013). IHC ; Human . Read more (PubMed: 23542458) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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