Application notesPeptide ELISA: Antibody detection limit dilution 1/4000.
WB: Preliminary experiments in Human Kidney, Liver and Placenta lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). Predicted molecular weight: 37 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionPotential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.
Tissue specificityWidely expressed. Frequently down-regulated in tumor cell lines.
Sequence similaritiesContains 1 Ras-associating domain. Contains 1 SARAH domain.