Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Accession
    • Species
      Rat

Associated products

Specifications

Our Abpromise guarantee covers the use of ab98259 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Purity
    >90% by SDS-PAGE.

  • Form
    Liquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • 5 HT 1A
    • 5 HT receptor 1A
    • 5 HT1A
    • 5 HT1A receptor
    • 5 hydroxytryptamine (serotonin) receptor 1A
    • 5 hydroxytryptamine (serotonin) receptor 1A G protein coupled
    • 5 hydroxytryptamine receptor 1A
    • 5-HT-1A
    • 5-HT1A
    • 5-hydroxytryptamine receptor 1A
    • 5HT 1A
    • 5HT 1A receptor
    • 5HT receptor 1A
    • 5HT1a
    • 5HT1A_HUMAN
    • ADRB2RL1
    • ADRBRL1
    • G 21
    • G protein coupled receptor
    • G-21
    • Gpcr 18
    • Gpcr18
    • Guanine nucleotide binding regulatory protein-coupled receptor
    • Htr1a
    • PFMCD
    • Serotonin 1A receptor
    • Serotonin 5HT1A receptor
    • Serotonin receptor 1A
    see all
  • Function
    This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

References

ab98259 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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