Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab32171 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General info

  • Alternative names
    • 5 Hydroxytryptamine 2C receptor
    • 5-HT-1C
    • 5-ht-1c receptor
    • 5-HT-2C
    • 5-HT1C
    • 5-HT2C
    • 5-HTR2C
    • 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
    • 5-hydroxytryptamine receptor 1C
    • 5-hydroxytryptamine receptor 2C
    • 5HT1C
    • 5HT2C
    • 5HT2C_HUMAN
    • 5HTR2C
    • 5Hydroxytryptamine 2C receptor
    • Htr1c
    • Htr2c
    • serotonin 1c receptor
    • serotonin 2c receptor
    • Serotonin 5-HT-2C receptor
    • Serotonin receptor 2C
    see all
  • FunctionThis is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • DomainThe PDZ domain-binding motif is involved in the interaction with MPDZ.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationCell membrane.
  • Information by UniProt

References for Rat 5HT2C Receptor peptide (ab32171)

This product has been referenced in:
  • Yu HJ & Yamaguchi A Endogenous serotonin acts on 5-HT2C-like receptors in key vocal areas of the brain stem to initiate vocalizations in Xenopus laevis. J Neurophysiol 103:648-58 (2010). Blocking . Read more (PubMed: 19955293) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"