Overview

Description

  • NatureSynthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab99036 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Calpain 2 antibody (ab88110)

  • Purity70 - 90% by HPLC.

  • FormLiquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • Calcium activated neutral proteinase
    • Calcium activated neutral proteinase 2
    • Calcium-activated neutral protease 2, catalytic subunit
    • Calcium-activated neutral proteinase 2
    • CALP80
    • Calpain 2 (m/II) large subunit
    • Calpain 2 catalytic subunit
    • Calpain 2 large catalytic subunit
    • Calpain 2 large subunit
    • Calpain 2, large [catalytic] subunit
    • Calpain large polypeptide L2
    • Calpain M type
    • Calpain M-type
    • Calpain-2 catalytic subunit
    • Calpain-2 large subunit
    • Calpain2
    • CAN2_HUMAN
    • CANP 2
    • CANP L2
    • CANP2
    • CANPL 2
    • CANPL2
    • CANPml
    • Capa2
    • CAPN 2
    • CAPN2
    • FLJ39928
    • M calpain
    • M calpin
    • M type
    • M-calpain
    • mCANP
    • Millimolar calpain
    • Millimolar-calpain
    see all
  • FunctionCalcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesBelongs to the peptidase C2 family.
    Contains 1 calpain catalytic domain.
    Contains 3 EF-hand domains.
  • Cellular localizationCytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca(2+) binding.
  • Information by UniProt

References for Rat Calpain 2 peptide (ab99036)

ab99036 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab99036.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"