• Nature

Associated products


Our Abpromise guarantee covers the use of ab47101 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-CGRP antibody (ab47027)

  • Form
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • Calcitonin/calcitonin related polypeptide alpha
    • Alpha type CGRP
    • Beta type CGRP
    • CALC1
    • CALC2
    • CALCA
    • CALCB
    • Calcitonin 1
    • Calcitonin 2
    • Calcitonin gene related peptide I
    • Calcitonin gene related peptide II
    • Calcitonin related polypeptide alpha
    • Calcitonin related polypeptide beta
    • CGRP
    • CGRP I
    • CGRP II
    • CGRP1
    • CGRP2
    • CT
    • Katacalcin
    • KC
    see all
  • Relevance
    CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed.
  • Cellular localization
    Endoplasmic reticulum and Secreted

References for Rat CGRP peptide (ab47101)

This product has been referenced in:
  • Tzabazis A  et al. Oxytocin receptor: Expression in the trigeminal nociceptive system and potential role in the treatment of headache disorders. Cephalalgia 36:943-50 (2016). Read more (PubMed: 26590611) »
  • Harrington AM  et al. Sprouting of colonic afferent central terminals and increased spinal MAP kinase expression in a mouse model of chronic visceral hypersensitivity. J Comp Neurol : (2012). Read more (PubMed: 22237807) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab47101.
Please use the links above to contact us or submit feedback about this product.


Sign up