The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 50% Sodium bicarbonate w/ up to 50% DMSO
ACCA orphan receptor
Adenylate cyclase constitutive activator
G protein coupled receptor 3
G-protein coupled receptor 3
Probable G protein coupled receptor GPR3
FunctionOrphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Has a potential role in modulating a number of brain functions, including behavioral responses to stress (By similarity), amyloid-beta peptide generation in neurons and neurite outgrowth (By similarity). Maintains also meiotic arrest in oocytes.
Tissue specificityExpressed predominantly in the central nervous system, and at low levels in the lung, kidney, testis, ovary and eye. Highly expressed in regions of the brain implicated in the Alzheimer disease.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.