Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Rat
    • Sequence
      ESEQAEQTAGQKRPLKNDEL

Specifications

Our Abpromise guarantee covers the use of ab89014 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Purity
    70 - 90% by HPLC.

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

  • Reconstitution
    Add ds Water or PBS buffer

General Info

  • Alternative names
    • 150 kDa oxygen regulated protein
    • 150 kDa oxygen-regulated protein
    • 170 kDa glucose regulated protein
    • 170 kDa glucose-regulated protein
    • DKFZp686N08236
    • FLJ94899
    • FLJ97572
    • glucose regulated protein 170
    • Grp 170
    • GRP-170
    • Grp170
    • HSP 12A
    • HSP12A
    • Hyou1
    • HYOU1_HUMAN
    • Hypoxia up regulated 1
    • hypoxia up-regulated 1 precursor
    • Hypoxia up-regulated protein 1
    • Hypoxia upregulated 1
    • Orp 150
    • ORP-150
    • Orp150
    • oxygen regulated protein (150kD)
    see all
  • Function
    Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding.
  • Tissue specificity
    Highly expressed in tissues that contain well-developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers.
  • Sequence similarities
    Belongs to the heat shock protein 70 family.
  • Cellular localization
    Endoplasmic reticulum lumen.
  • Information by UniProt

References

ab89014 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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