The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity70 - 90% by HPLC.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20ºC.
ReconstitutionAdd ds Water or PBS buffer
150 kDa oxygen regulated protein
150 kDa oxygen-regulated protein
170 kDa glucose regulated protein
170 kDa glucose-regulated protein
glucose regulated protein 170
Hypoxia up regulated 1
hypoxia up-regulated 1 precursor
Hypoxia up-regulated protein 1
Hypoxia upregulated 1
oxygen regulated protein (150kD)
FunctionHas a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding.
Tissue specificityHighly expressed in tissues that contain well-developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers.
Sequence similaritiesBelongs to the heat shock protein 70 family.