Rat Vesicle docking protein p115 peptide (ab39822)

Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesRat
    • SequenceMNFLRGVMGGQSAGPQH
    • Amino acids1 to 17

Specifications

Our Abpromise guarantee covers the use of ab39822 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

    Neutralising

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • General vesicular transport factor
    • General vesicular transport factor p115
    • P115
    • Protein USO1 homolog
    • TAP
    • Transcytosis associated protein
    • Transcytosis-associated protein
    • Uso1
    • USO1_HUMAN
    • VDP
    • Vesicle docking protein
    • Vesicle-docking protein
    see all
  • FunctionGeneral vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity.
  • Sequence similaritiesBelongs to the VDP/USO1/EDE1 family.
    Contains 10 ARM repeats.
  • DomainComposed of a globular head, an elongated tail (coiled-coil) and a highly acidic C-terminal domain.
  • Post-translational
    modifications
    Phosphorylated in a cell cycle-specific manner; phosphorylated in interphase but not in mitotic cells. Dephosphorylated protein associates with the Golgi membrane; phosphorylation promotes dissociation.
  • Cellular localizationCytoplasm > cytosol. Golgi apparatus membrane. Recycles between the cytosol and the Golgi apparatus during interphase. During interphase, the phosphorylated form is found exclusively in cytosol; the unphosphorylated form is associated with Golgi apparatus membranes.
  • Information by UniProt

References for Rat Vesicle docking protein p115 peptide (ab39822)

ab39822 has not yet been referenced specifically in any publications.

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