Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.
Contains 3 RRM (RNA recognition motif) domains.
Nucleus. Cytoplasm. Nuclear, in perinucleolar structures. Shuttles between nucleus and cytoplasm. Cytoplasm, at focal contacts and cell-cell contacts. Associated with myotubes during muscle differentiation.
Immunoprecipitation with ab157131 at 6µg/mg lysate. 1 mg of 293T whole cell lysate used for IP (20% of IP loaded). Western blot labelling RAVER1 with ab157131 at 1 µg/ml. Detected by chemiluminescence with exposure time of 30 seconds.