Overview

  • Product nameAnti-RbAp48 antibody
    See all RbAp48 primary antibodies
  • Description
    Mouse monoclonal to RbAp48
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-426 of Human RbAp48

Properties

Applications

Our Abpromise guarantee covers the use of ab55778 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCore histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
    • Sequence similaritiesBelongs to the WD repeat RBAP46/RBAP48/MSI1 family.
      Contains 6 WD repeats.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • CAF I p48 antibody
      • CAF-1 subunit C antibody
      • CAF-I 48 kDa subunit antibody
      • CAF-I p48 antibody
      • Chromatin assembly factor 1 subunit C antibody
      • Chromatin assembly factor I p48 subunit antibody
      • Chromatin assembly factor/CAF 1 p48 subunit antibody
      • Histone-binding protein RBBP4 antibody
      • MSI1 protein homolog antibody
      • Nucleosome-remodeling factor subunit RBAP48 antibody
      • NURF55 antibody
      • RbAp 48 antibody
      • RBAP48 antibody
      • RBBP-4 antibody
      • RBBP4 antibody
      • RBBP4_HUMAN antibody
      • Retinoblastoma binding protein 4 antibody
      • Retinoblastoma binding protein p48 antibody
      • Retinoblastoma-binding protein 4 antibody
      • Retinoblastoma-binding protein p48 antibody
      see all

    Anti-RbAp48 antibody images

    • RbAp48 antibody (ab55778) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human transitional cell carcinoma tissue.


    • Predicted band size : 48 kDa
      RbAp48 antibody (ab55778) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    References for Anti-RbAp48 antibody (ab55778)

    ab55778 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"