Overview

  • Product name
  • Description
    Rabbit polyclonal to Rbm15
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 146-395 of Human Rbm15 (NP_073605).

  • Positive control
    • WB: A431, H1299 and Hela cell lystes IHC-P: HeLa cells

Properties

Applications

Our Abpromise guarantee covers the use of ab96544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 107 kDa.
ICC/IF 1/100 - 1/200.

Target

  • Function
    May be implicated in HOX gene regulation.
  • Involvement in disease
    A chromosomal aberration involving RBM15 may be a cause of acute megakaryoblastic leukemia. Translocation t(1;22)(p13;q13) with MKL1. Although both reciprocal fusion transcripts are detected in acute megakaryoblastic leukemia (AMKL, FAB-M7), the RBM15-MKL1 chimeric protein has all the putative functional domains encoded by each gene and is the candidate oncogene.
  • Sequence similarities
    Belongs to the RRM Spen family.
    Contains 3 RRM (RNA recognition motif) domains.
    Contains 1 SPOC domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • One twenty two protein antibody
    • One-twenty two protein 1 antibody
    • OTT antibody
    • OTT1 antibody
    • Putative RNA-binding protein 15 antibody
    • RBM15 antibody
    • RBM15_HUMAN antibody
    • RNA binding motif protein 15 antibody
    • RNA-binding motif protein 15 antibody
    see all

Images

  • Anti-Rbm15 antibody (ab96544) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 107 kDa
  • ab96544, at a 1/200 dilution, staining Rbm15 in paraformaldehyde fixed HeLa cells by Immunofluorescence.
    Lower image is merged with DNA probe.

References

ab96544 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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