Overview

  • Product nameAnti-RBM22 antibody
    See all RBM22 primary antibodies
  • Description
    Rabbit polyclonal to RBM22
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 164-193 of Human RBM22 (NP_060517.1).

  • Positive control
    • Jurkat cell line lysate; 293 cell lysate transiently transfected with the RBM22 gene

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab124074 is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab124074 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 47 kDa.

Target

  • FunctionInvolved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses.
  • Sequence similaritiesBelongs to the SLT11 family.
    Contains 1 C3H1-type zinc finger.
    Contains 1 RRM (RNA recognition motif) domain.
  • DomainThe C-terminus RRM domain and the zinc finger motif are necessary for RNA-binding.
  • Cellular localizationNucleus. Cytoplasm. Mainly located in the nucleus. Translocated from the nucleus to the cytoplasm after heat shock cell treatment. May be shuttling between the nucleus and the cytosol.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cwc2 antibody
    • FLJ10290 antibody
    • fSAP47 antibody
    • Functional spliceosome associated protein 47 antibody
    • Pre mRNA splicing factor RBM22 antibody
    • Pre-mRNA-splicing factor RBM22 antibody
    • RBM 22 antibody
    • rbm22 antibody
    • RBM22_HUMAN antibody
    • RNA binding motif protein 22 antibody
    • RNA-binding motif protein 22 antibody
    • ZC3H16 antibody
    • Zinc finger CCCH domain containing protein 16 antibody
    • Zinc finger CCCH domain-containing protein 16 antibody
    see all

Anti-RBM22 antibody images

  • Anti-RBM22 antibody (ab124074) at 1/100 dilution + Jurkat cell line lysate at 35 µg

    Predicted band size : 47 kDa
  • All lanes : Anti-RBM22 antibody (ab124074) at 1/100 dilution

    Lane 1 : Nontransfected 293 cell lysate
    Lane 2 : 293 cell lysate transiently transfected with the RBM22 gene

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 47 kDa

References for Anti-RBM22 antibody (ab124074)

ab124074 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"