Overview

  • Product nameAnti-RBPJK antibody
    See all RBPJK primary antibodies
  • Description
    Mouse monoclonal to RBPJK
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 3-110 of Human RBPJK

Properties

Applications

Our Abpromise guarantee covers the use of ab55366 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionTranscriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.
    • Sequence similaritiesBelongs to the Su(H) family.
      Contains 1 IPT/TIG domain.
    • Cellular localizationNucleus. Cytoplasm. Mainly nuclear, upon interaction with RITA/C12orf52, translocates to the cytoplasm, down-regulating the Notch signaling pathway.
    • Information by UniProt
    • Database links
    • Alternative names
      • AI843960 antibody
      • CBF 1 antibody
      • CBF-1 antibody
      • CBF1 antibody
      • IGKJRB1 antibody
      • J kappa recombination signal binding protein antibody
      • J kappa-recombination signal-binding protein antibody
      • KBF2 antibody
      • NY REN 30 antigen antibody
      • RBP J kappa antibody
      • RBP-J antibody
      • RBP-J kappa antibody
      • RBP-JK antibody
      • Rbpj antibody
      • RBPJK antibody
      • RBPSUH antibody
      • Recombining binding protein suppressor of hairless antibody
      • Renal carcinoma antigen NY-REN-30 antibody
      • SUH_HUMAN antibody
      see all

    Anti-RBPJK antibody images



    • Predicted band size : 56 kDa

    References for Anti-RBPJK antibody (ab55366)

    ab55366 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"