Overview

  • Product name
  • Description
    Mouse polyclonal to RBPMS
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length RBPMS protein (Human)

  • Positive control
    • 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab67078 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: 1/500 - 1/1000. Detects a band of approximately 32 kDa (predicted molecular weight: 21 kDa).
    Detection Antibody Pair.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.
    • Tissue specificity
      Ubiquitously expressed, at various levels depending on the isoform and the tissue.
    • Sequence similarities
      Contains 1 RRM (RNA recognition motif) domain.
    • Domain
      The RRM domain is necessary for interaction with SMAD4. Both the RRM domain and the C-terminus are required for TGFB1/Smad-mediated transactivation activity.
    • Cellular localization
      Nucleus. Cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ32971 antibody
      • Heart and RRM expressed sequence antibody
      • Hermes antibody
      • RBP MS antibody
      • RBP-MS antibody
      • Rbpms antibody
      • RBPMS_HUMAN antibody
      • RNA binding protein gene with multiple splicing antibody
      • RNA-binding protein with multiple splicing antibody
      see all

    Images

    • All lanes : Anti-RBPMS antibody (ab67078) at 1/500 dilution

      Lane 1 : RBPMS transfected 293T cell lysate
      Lane 2 : Non-transfected 293T cell lysate

      Lysates/proteins at 25 µg/ml per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Predicted band size : 21 kDa
      Observed band size : 32 kDa (why is the actual band size different from the predicted?)

    References

    ab67078 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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