For the best experience on the Abcam website please upgrade to a modern browser such as
Storage instructions Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
Storage buffer Preservative: 0.09% Sodium azide Constituent: 99% PBS
Concentration information loading...
Purity Immunogen affinity purified
Purification notes ab116291 is purified through a protein A column, followed by peptide affinity purification.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 126 kDa.
Function Represses ICOS function, an essential costimulatory receptor for follicular T-cells. May act as an ubiquitin ligase that regulates ubiquitin-dependent control of AU-rich mRNAs by AUF1/HNRPD and HUR/ELAVL1.
Tissue specificity Widely expressed. Expressed at higher level in cerebellum, spleen, ovary and liver.
Sequence similarities Contains 1 C3H1-type zinc finger. Contains 1 RING-type zinc finger.
Cellular localization Cytoplasm. Localizes to cytosolic RNA granules, which are sites for regulating mRNA translation and decay, suggesting that it may bind RNA.
Information by UniProt
Anti-RC3H1 antibody images
References for Anti-RC3H1 antibody (ab116291)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"