Overview

  • Product nameAnti-RC3H1 antibody
    See all RC3H1 primary antibodies
  • Description
    Rabbit polyclonal to RC3H1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 1014-1043 of Human RC3H1 (NP_742068.1).

  • Positive control
    • NCI-H460 cell line lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab116291 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 126 kDa.

Target

  • FunctionRepresses ICOS function, an essential costimulatory receptor for follicular T-cells. May act as an ubiquitin ligase that regulates ubiquitin-dependent control of AU-rich mRNAs by AUF1/HNRPD and HUR/ELAVL1.
  • Tissue specificityWidely expressed. Expressed at higher level in cerebellum, spleen, ovary and liver.
  • Sequence similaritiesContains 1 C3H1-type zinc finger.
    Contains 1 RING-type zinc finger.
  • Cellular localizationCytoplasm. Localizes to cytosolic RNA granules, which are sites for regulating mRNA translation and decay, suggesting that it may bind RNA.
  • Information by UniProt
  • Database links
  • Alternative names
    • KIAA2025 antibody
    • Rc3h1 antibody
    • RC3H1_HUMAN antibody
    • RGD1563512 antibody
    • RING finger and C3H zinc finger protein 1 antibody
    • Ring Finger and CCCH type Zinc Finger Domain 1 antibody
    • RING finger protein 198 antibody
    • RNF198 antibody
    • Roquin antibody
    • RP5 1198E17.5 antibody
    • Sanroque protein antibody
    see all

Anti-RC3H1 antibody images

  • Anti-RC3H1 antibody (ab116291) at 1/100 dilution + NCI-H460 cell line lysates at 35 µg

    Predicted band size : 126 kDa

References for Anti-RC3H1 antibody (ab116291)

ab116291 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"