Overview

  • Product nameAnti-RCC2 antibody
    See all RCC2 primary antibodies
  • Description
    Rabbit polyclonal to RCC2
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Horse, Dog, Pig, Chimpanzee, Rhesus monkey, Orangutan, Bat, Elephant
  • Immunogen

    Synthetic peptide corresponding to a region between residues 475 and the C-terminus (residue 522) of Human RCC2 (NP_061185.1).

  • Positive control
    • Human basal cell carcinoma. Mouse teratoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab84481 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionRequired for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1.
    • Sequence similaritiesContains 7 RCC1 repeats.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localizationNucleus > nucleolus. Chromosome > centromere. Cytoplasm > cytoskeleton > spindle. Appears in the nucleus at G2, then concentrates at the inner centromere region of chromosomes during prophase. Redistributes to the midzone of the mitotic spindle during anaphase. Here, the protein covers the entire equatorial diameter from cortex to cortex.
    • Information by UniProt
    • Database links
    • Alternative names
      • KIAA1470 antibody
      • Protein RCC2 antibody
      • RCC 2 antibody
      • RCC1 like protein TD 60 antibody
      • RCC1-like protein TD-60 antibody
      • RCC2 antibody
      • RCC2_HUMAN antibody
      • Regulator of chromosome condensation 2 antibody
      • TD60 antibody
      • Telophase disk protein of 60 kDa antibody
      see all

    Anti-RCC2 antibody images

    • ab84481, at 1/500 dilution, staining RCC2 in formalin-fixed, paraffin-embedded human basal cell carcinoma by Immunohistochemistry, using DAB detection.
    • ab84481, at 1/100 dilution, staining RCC2 in formalin-fixed, paraffin-embedded mouse teratoma by Immunohistochemistry, using DAB detection.

    References for Anti-RCC2 antibody (ab84481)

    ab84481 has not yet been referenced specifically in any publications.

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    Thank you for contacting Abcam regarding our Anti-RCC2 antibody ab84481.


    Some of our products are made in house and others we obtain from outside laboratories. In this case, ab84481 is sourced from another laboratory, however it is not Ce...

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