Overview

  • Product nameAnti-RCC2 antibody
    See all RCC2 primary antibodies
  • Description
    Rabbit polyclonal to RCC2
  • Tested applicationsSuitable for: IP, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide within residues: IRSLACGKSS IIVAADESTI SWGPSPTFGE LGYGDHKPKS STAAQEVKTL, corresponding to internal sequence amino acids 432-481 of Human RCC2 (NP_061185)

  • Positive control
    • 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab86337 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP 1/500.
WB Use a concentration of 1 µg/ml. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionRequired for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1.
  • Sequence similaritiesContains 7 RCC1 repeats.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationNucleus > nucleolus. Chromosome > centromere. Cytoplasm > cytoskeleton > spindle. Appears in the nucleus at G2, then concentrates at the inner centromere region of chromosomes during prophase. Redistributes to the midzone of the mitotic spindle during anaphase. Here, the protein covers the entire equatorial diameter from cortex to cortex.
  • Information by UniProt
  • Database links
  • Alternative names
    • KIAA1470 antibody
    • Protein RCC2 antibody
    • RCC 2 antibody
    • RCC1 like protein TD 60 antibody
    • RCC1-like protein TD-60 antibody
    • RCC2 antibody
    • RCC2_HUMAN antibody
    • Regulator of chromosome condensation 2 antibody
    • TD60 antibody
    • Telophase disk protein of 60 kDa antibody
    see all

Anti-RCC2 antibody images

  • Anti-RCC2 antibody (ab86337) at 1 µg/ml + 293T cell lysate at 10 µg

    Secondary
    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size : 56 kDa
  • IP using ab86337 at 2 ug/ml of Mouse brain homogenate

References for Anti-RCC2 antibody (ab86337)

ab86337 has not yet been referenced specifically in any publications.

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