Overview

  • Product nameAnti-RDH11 antibody
    See all RDH11 primary antibodies
  • Description
    Rabbit polyclonal to RDH11
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptides to N terminal sequence MVELMFP (amino acids 1-7) and the C terminal sequence LLGLPID (amino acids 312-318) of Human RDH11

  • Positive control
    • Human kidney tissue

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab85849 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 35 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • FunctionExhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected.
  • Tissue specificityPredominantly expressed in the epithelial cells of prostate, in both basal and luminal secretory cell populations. Expressed at low levels in spleen, thymus, testis, ovary, small intestine, colon, peripherical blood leukocytes, kidney, adrenal gland and fetal liver. Not detected in prostatic fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes.
  • Sequence similaritiesBelongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Post-translational
    modifications
    Not glycosylated.
  • Cellular localizationEndoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Androgen regulated short chain dehydrogenase/reductase 1 antibody
    • Androgen-regulated short-chain dehydrogenase/reductase 1 antibody
    • ARSDR1 antibody
    • AU045252 antibody
    • C85936 antibody
    • CGI 82 antibody
    • FLJ32633 antibody
    • HCBP12 antibody
    • HCV core binding protein antibody
    • HCV core binding protein HCBP12 antibody
    • HCV core-binding protein HCBP12 antibody
    • MDT1 antibody
    • Prostate short chain dehydrogenase/reductase 1 antibody
    • Prostate short-chain dehydrogenase/reductase 1 antibody
    • PSDR1 antibody
    • RALR1 antibody
    • RDH11 antibody
    • RDH11_HUMAN antibody
    • Retinal reductase 1 antibody
    • retinol dehydrogenase 11 (all trans/9 cis/11 cis) antibody
    • Retinol dehydrogenase 11 antibody
    • SCALD antibody
    • SDR7C1 antibody
    • Short chain dehydrogenase/reductase family 7C, member 1 antibody
    see all

Anti-RDH11 antibody images

  • Formalin fixed and paraffin embedded human kidney tissue labelled with ab85849 at 5 µg/ml.

References for Anti-RDH11 antibody (ab85849)

ab85849 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab85849.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"