Overview

  • Product nameAnti-RDHE2 antibody
    See all RDHE2 primary antibodies
  • Description
    Rabbit polyclonal to RDHE2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Guinea pig, Cat
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 180-229 (GLSGVNGLAD YCASKFAAFG FAESVFVETF VQKQKGIKTT IVCPFFIKTG) of Human RDHE2 (NP_620419).

  • Positive control
    • Transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab87071 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 34 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionOxidoreductase with strong preference for NAD. Active in both the oxidative and reductive directions. Oxidizes all-trans-retinol in all-trans-retinaldehyde. No activity was detected with 11-cis-retinol or 11-cis-retinaldehyde as substrates with either NAD+/NADH or NADP+/NADPH.
  • Tissue specificityDetected in adult lung. Detected at low levels in adult brain, heart, testis, placenta, cervix, pancreas, uterus, stomach, rectum, small intestine, colon, esophagus, thymus, skin, and skin keratinocyte. Expression is higher in psoriasis lesions relative to unaffected skin from psoriasis patients. Detected in fetal kidney, skin and lung.
  • PathwayCofactor metabolism; retinol metabolism.
  • Sequence similaritiesBelongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Cellular localizationEndoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EPHD 2 antibody
    • EPHD-2 antibody
    • EPHD2 antibody
    • Epidermal retinal dehydrogenase 2 antibody
    • Epidermal retinol dehydrogenase 2 antibody
    • FLJ33105 antibody
    • RDH E2 antibody
    • RDH#2 antibody
    • RDH-E2 antibody
    • RDHE2_HUMAN antibody
    • Retinal short chain dehydrogenase reductase 2 antibody
    • Retinal short chain dehydrogenase reductase antibody
    • Retinal short-chain dehydrogenase reductase 2 antibody
    • retSDR2 antibody
    • Sdr16c5 antibody
    • Short chain dehydrogenase/reductase family 16C member 5 antibody
    • Short-chain dehydrogenase/reductase family 16C member 5 antibody
    see all

Anti-RDHE2 antibody images

  • Anti-RDHE2 antibody (ab87071) at 1 µg/ml (in 5% skim milk / PBS buffer) + Transfected 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 34 kDa
    Observed band size : 34 kDa
    Additional bands at : 48 kDa. We are unsure as to the identity of these extra bands.

References for Anti-RDHE2 antibody (ab87071)

ab87071 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"