Overview

  • Product nameAnti-REA antibody
    See all REA primary antibodies
  • Description
    Rabbit polyclonal to REA
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rabbit, Guinea pig, Rhesus monkey, Gorilla, Orangutan, Elephant
  • Immunogen

    Synthetic peptide corresponding to a region between residues 1 and 50 of Human REA (NP_009204.1)

  • Positive control
    • Human breast Carcinoma, Human Ovarian Carcinoma or Human Stomach Adenocarcinoma tissue.
  • General notes

    Shelf Life: 1 year from date of receipt

    The Alexa Fluor® 488 variant is available.

Properties

Applications

Our Abpromise guarantee covers the use of ab82547 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500.
    Epitope exposure with citrate buffer will enhance staining and is recommended


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionActs as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
    • Sequence similaritiesBelongs to the prohibitin family.
    • Developmental stageLevels of expression in fibroblasts decrease heterogeneously during cellular aging.
    • Cellular localizationMitochondrion inner membrane. Cytoplasm. Nucleus. Also cytoplasmic and nuclear.
    • Information by UniProt
    • Database links
    • Alternative names
      • B cell receptor associated protein BAP37 antibody
      • B-cell receptor-associated protein BAP37 antibody
      • BAP antibody
      • Bap37 antibody
      • BCAP 37 antibody
      • D prohibitin antibody
      • D-prohibitin antibody
      • p22 antibody
      • Phb2 antibody
      • PHB2_HUMAN antibody
      • PNAS 141 antibody
      • Prohibitin 2 antibody
      • Prohibitin-2 antibody
      • Repressor of estrogen receptor activity antibody
      see all

    Anti-REA antibody images

    • ab82547, at a 1:250 dilution, staining Human REA in breast adenocarcinoma, using Immunohistochemistry, Formalin/PFA-fixed paraffin-embedded tissue.
    • ab82547, at 1:250 dilution, staining human REA in ovarian carcinoma, using Immunohistochemistry, Formalin/PFA-fixed paraffin-embedded tissue.

    References for Anti-REA antibody (ab82547)

    ab82547 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"