Overview

  • Product nameAnti-REA antibody
    See all REA primary antibodies
  • Description
    Rabbit polyclonal to REA
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 45-298 of Human REA (NP_009204)

  • Positive control
    • H1299 and HeLa whole cell lysates; A431 cells; 293T, HepG2, Molt-4 and Raji cell lines

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab97538 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 33 kDa.
ICC/IF 1/100 - 1/200.

Target

  • FunctionActs as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
  • Sequence similaritiesBelongs to the prohibitin family.
  • Developmental stageLevels of expression in fibroblasts decrease heterogeneously during cellular aging.
  • Cellular localizationMitochondrion inner membrane. Cytoplasm. Nucleus. Also cytoplasmic and nuclear.
  • Information by UniProt
  • Database links
  • Alternative names
    • B cell receptor associated protein BAP37 antibody
    • B-cell receptor-associated protein BAP37 antibody
    • BAP antibody
    • Bap37 antibody
    • BCAP 37 antibody
    • D prohibitin antibody
    • D-prohibitin antibody
    • p22 antibody
    • Phb2 antibody
    • PHB2_HUMAN antibody
    • PNAS 141 antibody
    • Prohibitin 2 antibody
    • Prohibitin-2 antibody
    • Repressor of estrogen receptor activity antibody
    see all

Anti-REA antibody images

  • All lanes : Anti-REA antibody (ab97538) at 1/1000 dilution

    Lane 1 : H1299 whole cell lysate
    Lane 2 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 33 kDa
  • Immunofluorescence analysis of paraformaldehyde-fixed A431, using ab97538 at 1/200 dilution (1) and merged with DNA probe (2).

References for Anti-REA antibody (ab97538)

ab97538 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"