Our tissue slides and tissue microarrays are useful for the identification and localization of proteins or RNA in normal or disease state tissue samples.
Our tissue slides and microarrays:
Are comprised of formalin-fixed, paraffin-embedded (FFPE) tissues from a wide variety of tissue sources, many of which are difficult to obtain
Are suitable for use in immunohistochemistry (IHC), in situ hybridization (ISH) and in situ PCR assays
Enable rapid comparison of gene or protein expression in different tissues
Can be used as positive staining controls for antibody validation and DNA or RNA isolation
Documentation relating to tissue clinical history is available from our Scientific Support team.
We offer a range of over 240 tissues slides prepared from both normal and diseased organs, such as spleen, kidney, angioma and Alzheimer's disease tissues. Our slides contain tissues from a range of species including human, mouse and rat. Our slides are comprised of FFPE tissue sections that are approximately 5 µm thick.
A tissue microarray (TMA) consists of a histology slide on which representative tissue samples (cores) from a selection of different cases are assembled. TMAs are a valuable tool for investigations requiring a large number of histology sections, offering several advantages over the use of serial sections including:
Better utilization of tissue sections, particularly when these are a scarce resource
Improved experimental consistency as identical experimental conditions are used for each core
Decreased reagent use and the associated cost savings
Options for analysis at the DNA, RNA or protein level (using FISH, mRNA ISH and IHC, respectively)
Abcam offers tissue microarrays containing up to 228 tissue samples per slide from human, mouse and rat tissues. Our portfolio covers a wide range of organs and disease states. Control cores, pathology and disease states are provided where relevant. All tissues were fixed in 10% neutral buffered formalin for 24 to 48 hours. All of our tissue microarrays:
are freshly cut (sectioned upon receipt of an order)
homogenous for clear analysis of morphology
demonstrate low specimen loss (>90% core retention rates)