Anti-REBOV GP antibody (ab190658)
Key features and details
- Rabbit polyclonal to REBOV GP
- Suitable for: WB
- Reacts with: Reston ebolavirus
- Isotype: IgG
Overview
-
Product name
Anti-REBOV GP antibody -
Description
Rabbit polyclonal to REBOV GP -
Host species
Rabbit -
Specificity
ab190658 detects recombinant REBOV GP without the transmembrane region (REBOV rGPdTM). No cross reactivity to Sudan ebolavirus (SEBOV) GP, Zaire ebolavirus (ZEBOV) GP, Bundibugyo (BEBOV) GP or Marburg (MARV) GP, was observed in Western blot analysis. -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Reston ebolavirus -
Immunogen
Synthetic peptide corresponding to REBOV GP. (Reston Ebola virus glycoprotein).
Database link: Q66800 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Constituent: 100% PBS -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab190658 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
Use a concentration of 0.5 µg/ml. Predicted molecular weight: 42 kDa.
|
Notes |
---|
WB
Use a concentration of 0.5 µg/ml. Predicted molecular weight: 42 kDa. |
Target
-
Relevance
REBOV GP seems to possess an anti-inflammatory activity as it can reverse the barrier-decreasing effects of TNF alpha. Might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production. Does not seem to be involved in activation of primary macrophages. Does not seem to interact specifically with neutrophils. Delta-peptide does not seem to be involved in activation of primary macrophages B REBOV GP is a homodimer; disulfide-linked. The homodimers are linked by two disulfide bonds in a parallel orientation. Delta-peptide is a monome -
Cellular localization
Secreted -
Alternative names
- pre-sGP antibody
- Pre-small/secreted glycoprotein antibody
- small/secreted non-structural glycoprotein antibody
- structural glycoprotein antibody
Images
-
All lanes : Anti-REBOV GP antibody (ab190658) at 0.05 µg/ml
Lane 1 : REBOV rGPdTM supernatant at 15 µl
Lane 2 : ZEBOV rGPdTM at 0.2 µg
Lane 3 : SEBOV rGPdTM at 0.2 µg
Lane 4 : MARV rGPdTM at 0.2 µg
Lane 5 : BEBOV rGPdTM at 0.2 µg
Predicted band size: 42 kDaREBOV GP is visualized as a broad band representing differing glycosylation patterns.
-
All lanes : Anti-REBOV GP antibody (ab190658) at 0.5 µg/ml
Lane 1 : REBOV rGPdTM supernatant at 15 µl
Lane 2 : ZEBOV rGPdTM at 0.2 µg
Lane 3 : SEBOV rGPdTM at 0.2 µg
Lane 4 : MARV rGPdTM at 0.2 µg
Lane 5 : BEBOV rGPdTM at 0.2 µg
Predicted band size: 42 kDaREBOV GP is visualized as a broad band representing differing glycosylation patterns.
Datasheets and documents
-
Datasheet download
References (0)
ab190658 has not yet been referenced specifically in any publications.