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| Product Name | RECK antibody - First spacer region |
| | See all RECK antibodies (4)... |
| Product type | Primary antibodies |
| Description | Rabbit polyclonal to RECK - First spacer region |
| Immunogen | Synthetic peptide based on the first spacer region of human RECK, before the first EGF like domain.(Peptide available as ab41253.) |
| Reacts with
(species key) | Hu |
| Specificity | ab28271 recognises RECK. We have a range of domain specific antibodies for this target. For a full list please see all RECK antibodies |
| Tested applications
(see key) | WB |
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| Abreviews | |
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| Application notes
(see key) | Recommended dilutions
WB: 1/1000, when using colorimetric substrates such as BCIP/NBT - 1/5000, when using chemiluminescent substrates. Predicted molecular weight: 106 kDa. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Cellular localization | Cell membrane; lipid-anchor; GPI-anchor. |
| Research areas | Cell Biology >> Proteolysis / Ubiquitin >> Protease inhibitors >> Serine protease inhibitors >> RECK
Cancer >> Oncoproteins/suppressors >> Tumor suppressors >> Other |
| Relevance | RECK is a cysteine rich, extracellular protein with protease inhibitor like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase 9, a key enzyme involved in tumor invasion and metastasis.
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| Database links | The links below go to external sites and will open in a new browser window |
| Raised in | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Immunogen affinity purified |
| Storage buffer | Preservative: 0.05% Sodium Azide
Constituents: 50% Glycerol Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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| Form | Liquid |
| Concentration | 1.000 mg/ml |
| Storage instructions | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles. |
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this RECK antibody - First spacer region is on this datasheet. But please do contact us if you would like any reassurance! |
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| Search PubMed (MEDLINE) for references to RECK |
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