Recombinant Bottlenose Dolphin IL1 alpha protein (ab117469)

Overview

Description

  • NatureRecombinant
  • SourceYeast
  • Amino Acid Sequence
    • AccessionQ9TTK2
    • SpeciesBottlenose Dolphin
    • SequenceSNMKYNFIKL IQQQYILNDA LHQSIVLHPS GQHLMAAALN NLDEAVEFDI AAYTSGDDTQ LPVTLRISKT QLFVCAQNEG EPVLLKEMPE TPQTIKDETD LLFLWSNHGS MQHFKSVAHP KLYFATKGEK LVHLARGPPS IIDFQL
    • Molecular weight17 kDa
    • Amino acids120 to 265

Specifications

Our Abpromise guarantee covers the use of ab117469 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    ab117469 was purified by ion exchange chromatography.
  • FormLyophilised
  • Additional notesab117469 is stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Please see notes section.

    Constituents: 89% PBS, 10% Trehalose

  • ReconstitutionReconstitute with sterile PBS containing at least 0.1% carrier protein.

General Info

  • Alternative names
    • BAF
    • FAF
    • Hematopoietin 1
    • Hematopoietin-1
    • IL 1 alpha
    • IL 1A
    • IL-1 alpha
    • Il-1a
    • IL1
    • IL1 ALPHA
    • IL1A
    • IL1A_HUMAN
    • IL1F1
    • Interleukin 1 alpha
    • Interleukin-1 alpha
    • Interleukin1 alpha
    • LAF
    • LEM
    • Preinterleukin 1 alpha
    • Pro interleukin 1 alpha
    see all
  • FunctionProduced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
  • Sequence similaritiesBelongs to the IL-1 family.
  • DomainThe similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
  • Cellular localizationSecreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
  • Information by UniProt

References for Recombinant Bottlenose Dolphin IL1 alpha protein (ab117469)

ab117469 has not yet been referenced specifically in any publications.

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