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Full length protein
Amino Acid Sequence
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
The specific activity was found to be 200 IU/mg.
One unit is defined as 1µmol of NAD+ production per minute under the assay conditions (25°C, pH 7.0).
Purity is greater than 95.0% as determined by RP-HPLC and SDS-PAGE.
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 0.61mM Potassium phosphate
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Reconstitute in sterile 18MO-cm H2O not less than 100 µg/ml.
- Cell proliferation-inducing gene 19 protein
- L lactate dehydrogenase B chain
Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.
Involvement in disease
Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:612933]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.
Belongs to the LDH/MDH superfamily. LDH family.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"