Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Cow

Specifications

Our Abpromise guarantee covers the use of ab90853 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50mM Sodium chloride, 40mM HEPES, 3mM DTE (1, 4-Dithioerythritol), 0.1mM GDP, pH 7.2

General Info

  • Alternative names
    • 1A
    • FLJ41411
    • GDI-1
    • gdi1
    • GDIA_HUMAN
    • GDIL
    • GDP dissociation inhibitor 1
    • Guanosine diphosphate dissociation inhibitor 1
    • Mental retardation X-linked 41
    • Mental retardation X-linked 48
    • MRX41
    • MRX48
    • Oligophrenin 2
    • Oligophrenin-2
    • OPHN2
    • Protein XAP 4
    • Protein XAP-4
    • Protein XAP4
    • Rab GDI alpha
    • Rab GDP dissociation inhibitor alpha
    • RABGD1A
    • RABGDIA
    • XAP 4
    see all
  • Function
    Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
  • Tissue specificity
    Brain; predominant in neural and sensory tissues.
  • Involvement in disease
    Defects in GDI1 are the cause of mental retardation X-linked type 41 (MRX41) [MIM:300104]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
    Defects in GDI1 are the cause of mental retardation X-linked type 48 (MRX48) [MIM:300104]; also known as MRX3.
  • Sequence similarities
    Belongs to the Rab GDI family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

References

ab90853 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab90853.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up